Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954462 | 0.83 | SRC (0.33) | SRCALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10609449 | 0.81 | GABRA1 (0.41) | SRCALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL10816328 | 0.80 | CA1 (0.39) | SRCALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL88528 | 0.75 | SRC (0.48) | SRCALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL10889949 | 0.73 | SRC (0.47) | SRCALDH1A1MAPTTSHRSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL9066051 | 0.73 | SRC (0.47) | SRCALDH1A1MAPTTSHRSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL28159633 | 0.73 | SRC (0.47) | SRCALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL5140754 | 0.71 | NPC1 (0.40) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9555419 | 0.70 | ALDH1A1 (0.33) | ALDH1A1MAPTHDAC8TSHR | |
| SCHEMBL10833260 | 0.69 | MAPT (0.32) | ALDH1A1MAPTHDAC8TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498605-A | ANTIISCHEMIC AGENTS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-03-12 | — | — | US | disclosed |
| WO-1994002497-A1 | SULFO-DERIVATIVES OF ADENOSINE | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1994-02-03 | — | — | WO | disclosed |