Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 4/20 | 0.39 |
| ▸ | F10 | P00742 | 6/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | CCR4 | P51679 | 5/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954624 | 0.88 | F10 (0.41) | F10PLAUF2PRSS1HCRTR1 | |
| SCHEMBL8954816 | 0.84 | F10 (0.39) | AKR1C3F10F2CCR4GRM2 | |
| SCHEMBL8954946 | 0.83 | F10 (0.45) | AKR1C3F10PLAUF2PRSS1 | |
| SCHEMBL8954654 | 0.80 | F10 (0.59) | F10PLAUF2 | |
| SCHEMBL8955009 | 0.79 | HTT (0.52) | F10PLAUF2PRSS1ALDH1A1 | |
| SCHEMBL8954706 | 0.78 | F10 (0.52) | F10PLAUF2 | |
| SCHEMBL9710120 | 0.78 | F10 (0.38) | AKR1C3F10F2PRSS1CCR4 | |
| SCHEMBL9710875 | 0.77 | F10 (0.46) | AKR1C3F10F2PRSS1CCR4 | |
| SCHEMBL8955020 | 0.76 | ALDH1A1 (0.38) | AKR1C3F10PLAUF2PRSS1 | |
| SCHEMBL8954788 | 0.76 | ALDH1A1 (0.37) | AKR1C3F10AKR1C1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |
| EP-0511347-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | Pentapharm A.G. (CH) | 1992-11-04 | — | — | EP | disclosed |
| WO-1992008709-A1 | META-SUBSTITUTED PHENYL ALANINE DERIVATIVES | PENTAPHARM AG (CH) | 1992-05-29 | — | — | WO | disclosed |