Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 3/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954788 | 0.84 | ALDH1A1 (0.37) | ALDH1A1HTTPKMSMN1; SMN2LMNA | |
| SCHEMBL8955009 | 0.82 | HTT (0.52) | ALDH1A1HTTMCOLN3TSHRPKM | |
| SCHEMBL8954656 | 0.76 | AKR1C3 (0.39) | ALDH1A1SMN1; SMN2KMT2AF10AKR1C3 | |
| SCHEMBL8954946 | 0.75 | F10 (0.45) | MCOLN3LMNAF10AKR1C3PLAU | |
| SCHEMBL8954816 | 0.74 | F10 (0.39) | ALDH1A1HTTSMN1; SMN2GAAKMT2A | |
| SCHEMBL9710120 | 0.72 | F10 (0.38) | ALDH1A1HTTSMN1; SMN2KMT2AF10 | |
| SCHEMBL9664400 | 0.71 | ALDH1A1 (0.47) | ALDH1A1HTTMCOLN3TSHRF10 | |
| Bicarbonate SCHEMBL9665131 | 0.71 | F10 (0.57) | F10PLGPLAUF2PRSS1 | |
| SCHEMBL8954996 | 0.70 | F10 (0.39) | F10PLAU | |
| SCHEMBL9710123 | 0.69 | F10 (0.37) | ALDH1A1F10KAT6APLGPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |