SCHEMBL8955114

SCHEMBL8955114

COc1ccc(O[Si](O[SiH2])(Oc2ccc(OC)cc2)Oc2ccc(OC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
CA7 P43166 2/20 0.52
CA9 Q16790 2/20 0.52
CA12 O43570 1/20 0.52
CA14 Q9ULX7 1/20 0.52
ACHE P22303 1/20 0.44
ALDH1A1 P00352 3/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 3/20 0.42
MAPK1 P28482 2/20 0.42
KDM4E B2RXH2 1/20 0.41
NPC1 O15118 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
THRB P10828 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7859077 0.81 ACHE (0.44) CA1CA2CA9ACHEALDH1A1
SCHEMBL7852131 0.75 LTA4H (0.41) CA1CA2CA9ALDH1A1KMT2A
1,4-Dimethoxybenzene SCHEMBL21802643 0.72 CA1 (1.00) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL8489 0.72 CA1 (1.00) CA1CA2CA7CA9CA12
SCHEMBL11233031 0.72 CA1 (0.61) CA1CA2CA7CA9CA12
SCHEMBL8955110 0.71 CA1 (0.52) CA1CA2CA7CA9CA12
SCHEMBL9224695 0.70 CA1 (0.58) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL11373286 0.67 CA1 (0.85) CA1CA2CA7CA9CA12
SCHEMBL9301 0.66
SCHEMBL4779881 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5484685-A Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI, LTD. (JP) 1996-01-16 US disclosed
EP-0464959-B1 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof HITACHI CHEMICAL CO LTD (JP) 1995-12-20 EP disclosed
EP-0284370-B1 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof HITACHI CHEMICAL CO LTD (JP) 1994-06-22 EP disclosed
EP-0366440-B1 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI CHEMICAL CO LTD (JP) 1994-06-08 EP disclosed
EP-0357360-B1 Naphthalocyanine derivatives, production thereof and optical recording medium using the same HITACHI CHEMICAL CO LTD (JP) 1994-06-08 EP disclosed
US-5268485-A A 1,3-diiminobenz(f)isoindoline derivative HITACHI CHEMICAL COMPANY, LTD. (JP) 1993-12-07 US disclosed
EP-0378336-B1 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof HITACHI CHEMICAL CO LTD (JP) 1993-12-01 EP disclosed
US-5219706-A Naphthalocyanine derivative and production process thereof, as well as optical information recording media using the derivatives and production process thereof HITACHI, LTD. (JP) 1993-06-15 US disclosed
US-5110968-A NAPHTHALOCYANINE DERIVATIVES, PRODUCTION THEREOF, OPTICAL RECORDING MEDIUM USING THE SAME, AND PRODUCTION THEREOF HITACHI, CHEMICAL COMPANY LTD. (JP) 1992-05-05 US disclosed
US-5075203-A Containing sulfone groups; absorbers of laser beams HITACHI CHEMICAL COMPANY, LTD. (JP) 1991-12-24 US disclosed
US-5039600-A Solubility in organic solvents, absorption of semiconductor laser light HITACHI CHEMICAL COMPANY, LTD. (JP) 1991-08-13 US disclosed
EP-0378336-A1 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof Hitachi Chemical Co., Ltd. (JP) 1990-07-18 EP disclosed
EP-0366440-A2 Naphthalocyanine derivatives, production thereof, optical recording medium using the same, and production thereof Hitachi Chemical Co., Ltd. (JP) 1990-05-02 EP disclosed
EP-0357360-A2 Naphthalocyanine derivatives, production thereof and optical recording medium using the same Hitachi Chemical Co., Ltd. (JP) 1990-03-07 EP disclosed
EP-0284370-A2 Naphthalocyanine derivatives and production processes thereof, as well as optical information recording media using the derivatives and production processes thereof Hitachi Chemical Co., Ltd. (JP) 1988-09-28 EP disclosed