Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.43 |
| ▸ | PLG | P00747 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956093 | 0.99 | F10 (0.44) | F10PLGST14F2PLAU | |
| Bicarbonate SCHEMBL9665066 | 0.86 | F10 (0.45) | F10PLGF2PLAUPRSS1 | |
| SCHEMBL8956282 | 0.86 | MAPK1 (0.40) | TP53POLBALOX15TSHRGFER | |
| Hydrochloric Acid SCHEMBL8954922 | 0.82 | F10 (0.51) | F10PLGST14F2PLAU | |
| SCHEMBL8954706 | 0.80 | F10 (0.52) | F10PLGST14F2PLAU | |
| Iodide SCHEMBL8955180 | 0.77 | F10 (0.53) | F10PLGST14F2PLAU | |
| SCHEMBL8956082 | 0.76 | F10 (0.54) | F10PLGST14F2PLAU | |
| Iodide SCHEMBL9710508 | 0.75 | F10 (0.51) | F10PLGF2PLAUPRSS1 | |
| SCHEMBL8954875 | 0.73 | F10 (0.44) | F10PLGST14F2PLAU | |
| SCHEMBL8954767 | 0.71 | F10 (0.50) | F10PLGST14F2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518735-A | ANTICOAGULANTS ADMINISTERED BY MOUTH | PENTAPHARM AG (CH) | 1996-05-21 | — | — | US | disclosed |