Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PPID | Q08752 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27412717 | 0.82 | TAS1R3 (0.49) | TGFBR1TAS1R3TAS1R1ALDH1A1NOS3 | |
| SCHEMBL7098405 | 0.82 | TAS1R3 (0.49) | TGFBR1TAS1R3TAS1R1ALDH1A1NOS3 | |
| SCHEMBL9052340 | 0.79 | TAS1R3 (0.40) | TAS1R3TAS1R1TDP1ALDH1A1BIRC2 | |
| SCHEMBL9052342 | 0.79 | TAS1R3 (0.40) | TAS1R3TAS1R1TDP1ALDH1A1BIRC2 | |
| SCHEMBL3574775 | 0.77 | NPSR1 (0.48) | TGFBR1TDP1ALDH1A1TSHRPOLB | |
| SCHEMBL3574778 | 0.77 | NPSR1 (0.48) | TGFBR1TDP1ALDH1A1TSHRPOLB | |
| SCHEMBL13613767 | 0.77 | SMN1; SMN2 (0.56) | TAS1R3TAS1R1TDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15107083 | 0.76 | SMN1; SMN2 (0.49) | TAS1R3TAS1R1TDP1ALDH1A1BIRC2 | |
| SCHEMBL8032842 | 0.75 | TGFBR1 (0.67) | TGFBR1ALDH1A1FOLH1PLA2G2APLA2G5 | |
| SCHEMBL6242220 | 0.75 | TGFBR1 (0.67) | TGFBR1ALDH1A1FOLH1PLA2G2APLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8059586-A | — | — | None | — | — | JP | disclosed |
| JP-H0859586-A | N-(METH)ACRYLOYL-LEUCINE ALKYL ESTER, ITS PRODUCTION AND ITS POLYMER | AIBAITSU KK | 1996-03-05 | — | — | JP | disclosed |