Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17500076 | 0.81 | ALDH1A1 (0.48) | HIF1AALDH1A1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL4729047 | 0.80 | ALDH1A1 (0.45) | HIF1AALDH1A1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL29404283 | 0.79 | HSPA5 (0.55) | HIF1AALDH1A1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL8028498 | 0.79 | HSPA5 (0.55) | HIF1AALDH1A1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL29966261 | 0.77 | GLRA3 (0.43) | HIF1AALDH1A1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL7649239 | 0.77 | GLRA3 (0.43) | HIF1AALDH1A1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL466567 | 0.77 | CYP2C19 (0.50) | HIF1AALDH1A1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL30903568 | 0.77 | HSPA5 (0.66) | HIF1AALDH1A1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL39554 | 0.77 | HSPA5 (0.66) | HIF1AALDH1A1CYP1A2CYP2D6MAPK1 | |
| SCHEMBL29500375 | 0.77 | HSPA5 (0.66) | HIF1AALDH1A1CYP1A2CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0568819-B1 | Process for the preparation of 3-(hydroxyphenyl)-propionaldehydes and optionally the preparation of 3-(hydroxyphenyl)-propanols | BASF AG (DE) | 1996-01-03 | — | — | EP | disclosed |
| US-5304685-A | Preparation of 3-(hydroxyphenyl)propionaldehydes and their hydrogenation to 3-(hydroxyphenyl)propanols | BASF AKTIENGESELLSCHAFT (DE) | 1994-04-19 | — | — | US | disclosed |
| EP-0568819-A1 | Process for the preparation of 3-(hydroxyphenyl)-propionaldehydes and optionally the preparation of 3-(hydroxyphenyl)-propanols | BASF Aktiengesellschaft (DE) | 1993-11-10 | — | — | EP | disclosed |