SCHEMBL8955364

SCHEMBL8955364

C=C(C)C(=O)OC[SiH](Cl)OC

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
ALDH1A1 P00352 2/20 0.44
THRB P10828 1/20 0.42
POLB P06746 1/20 0.35
APEX1 P27695 1/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2113103 0.83 TSHR (0.48) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL1071909 0.81 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL2528099 0.79 TSHR (0.45) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL17059985 0.76 TSHR (0.50) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL8955366 0.73 THRB (0.46) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL16253927 0.72 THRB (0.48) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL2583635 0.72 TSHR (0.42) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL8955304 0.72 TSHR (0.47) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL2584392 0.71 TSHR (0.45) TSHRALDH1A1THRBPOLBAPEX1
SCHEMBL6037331 0.71 THRB (0.52) TSHRALDH1A1THRBPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187704-B2 Optical film, polarizing plate and image display device FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-7982953-B2 Antireflection film, and polarizing plate and image display device using the same FUJIFILM CORPORATION (JP) 2011-07-19 US disclosed
US-7622194-B2 use of a transparent support having specific physical properties during the spreading of a functional layer makes it possible to control the spread and the penetration of solvent and hence provide a good quality optical film having little coating defects, reducing impact of residual solvent; LCDs FUJIFILM CORPORATION (JP) 2009-11-24 US disclosed
US-7572516-B2 Antireflection film, and display device comprising the same FUJIFILM CORPORATION (JP) 2009-08-11 US disclosed
US-20090081447-A1 OPTICAL FILM, POLARIZING PLATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-03-26 US disclosed
US-20070291363-A1 Optical Film FUJIFILM CORPORATION (JP) 2007-12-20 US disclosed
US-20070048457-A1 Producing method of film having coated layer, film having coated layer, optical film, polarizing plate and liquid crystal display FUJI FILM CORPORATION (JP) 2007-03-01 US disclosed