Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955364 | 0.83 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL17059985 | 0.79 | TSHR (0.50) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL6037331 | 0.78 | THRB (0.52) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1071909 | 0.76 | TSHR (0.47) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL3064653 | 0.75 | — | — | |
| SCHEMBL692094 | 0.75 | TSHR (0.56) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL2584392 | 0.74 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL28595661 | 0.74 | TSHR (0.60) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL2528099 | 0.74 | TSHR (0.45) | TSHRTHRBALDH1A1TDP1POLB | |
| SCHEMBL1633952 | 0.74 | TSHR (0.59) | TSHRTHRBALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0777697-B1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORP (US) | 2001-09-19 | — | — | EP | claimed |
| EP-0777697-A4 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORP (US) | 1998-08-19 | — | — | EP | claimed |
| EP-0777697-A1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORPORATION (US) | 1997-06-11 | — | — | EP | claimed |
| US-5605999-A | SEALANT; HIGH STRENGTH, HEAT RESISTANCE; BLEND OF (UNSATURATED)ORGANOSILICON COMPOUND, (METH)ACRYLATE MONOMER AND PROMOTER | LOCTITE CORPORATION (US) | 1997-02-25 | — | — | US | claimed |
| WO-1996039458-A1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORPORATION (US) | 1996-12-12 | — | — | WO | claimed |
| US-8158735-B2 | Adhesive bonding system having adherence to low energy surfaces | LOCTITE (R&D) LIMITED (IE) | 2012-04-17 | — | — | US | disclosed |
| US-20100178520-A1 | ADHESIVE BONDING SYSTEM HAVING ADHERENCE TO LOW ENERGY SURFACES | LOCTITE (R&D) LIMITED (IE) | 2010-07-15 | — | — | US | disclosed |
| EP-1795544-B1 | High temperature, controlled strength anaerobic adhesive compositions curable under ambient environmental conditions | HENKEL LOCTITE CORP (US) | 2010-01-27 | — | — | EP | disclosed |
| US-7408012-B1 | Adhesive bonding systems having adherence to low energy surfaces | LOCTITE (R&D) LIMITED (IE) | 2008-08-05 | — | — | US | disclosed |
| EP-1795544-A2 | High temperature, controlled strength anaerobic adhesive compositions curable under ambient environmental conditions | Henkel Loctite Corporation (US) | 2007-06-13 | — | — | EP | disclosed |
| US-6884314-B2 | Conducive, silicone-based compositions with improved initial adhesion reduced microvoiding | HENKEL CORPORATION (US) | 2005-04-26 | — | — | US | disclosed |
| US-6828355-B1 | Resin-reinforced silicone compositions curable upon exposure to radiation in the electromagnetic spectrum, which when cured demonstrate improved elastomeric properties, such as tensile strength, modulus and elongation | HENKEL CORPORATION | 2004-12-07 | — | — | US | disclosed |
| US-20030164223-A1 | Conducive, silicone-based compositions with improved initial adhesion reduced microvoiding | Henkel IP & Holding GmbH (DE) | 2003-09-04 | — | — | US | disclosed |
| US-6391993-B1 | ADHESIVE; BLEND CONTAINING (METH)ACRYLATE, MALEIMIDE COMPOUNDAND DILUENTS | LOCTITE CORPORATION | 2002-05-21 | — | — | US | disclosed |
| EP-0777697-B1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORP (US) | 2001-09-19 | — | — | EP | disclosed |
| EP-0987306-A2 | Curable silicon sealant/adhesive compositions. | LOCTITE CORPORATION (US) | 2000-03-22 | — | — | EP | disclosed |
| EP-0777697-A4 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORP (US) | 1998-08-19 | — | — | EP | disclosed |
| EP-0777697-A1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORPORATION (US) | 1997-06-11 | — | — | EP | disclosed |
| US-5605999-A | SEALANT; HIGH STRENGTH, HEAT RESISTANCE; BLEND OF (UNSATURATED)ORGANOSILICON COMPOUND, (METH)ACRYLATE MONOMER AND PROMOTER | LOCTITE CORPORATION (US) | 1997-02-25 | — | — | US | disclosed |
| WO-1996039458-A1 | CURABLE SILICONE SEALANT/ADHESIVE COMPOSITIONS | LOCTITE CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |