Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 3/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.56 |
| ▸ | F10 | P00742 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 4/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | CA7 | P43166 | 4/20 | 0.51 |
| ▸ | CA9 | Q16790 | 4/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.50 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | SELE | P16581 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152540 | 0.90 | CA12 (0.58) | MEN1MAPTKMT2AESR1ESR2 | |
| SCHEMBL9938318 | 0.88 | MEN1 (0.70) | MEN1MAPTKMT2AF10F2 | |
| SCHEMBL149288 | 0.87 | CA12 (0.67) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL29890037 | 0.87 | CA12 (0.67) | ESR1ESR2CA12CA1CA2 | |
| SCHEMBL9937715 | 0.86 | TDP1 (0.63) | MEN1MAPTKMT2AF10F2 | |
| SCHEMBL8737053 | 0.85 | MEN1 (0.60) | MEN1MAPTKMT2AF10F2 | |
| SCHEMBL9938937 | 0.85 | SMN1; SMN2 (0.59) | MEN1MAPTKMT2AESR1ESR2 | |
| SCHEMBL930833 | 0.84 | MEN1 (0.62) | MEN1MAPTKMT2AF10F2 | |
| SCHEMBL3510175 | 0.83 | ESR1 (0.65) | MEN1KMT2AESR1ESR2L3MBTL1 | |
| SCHEMBL6829100 | 0.82 | LMNA (0.59) | MEN1MAPTKMT2AF10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552441-A | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS AND RESPIRATORY SYSTEM DISORDERS | ELI LILLY AND COMPANY (US) | 1996-09-03 | — | — | US | disclosed |
| US-5324743-A | Leukotriene B4 antagonists | ELI LILLY AND COMPANY (US) | 1994-06-28 | — | — | US | disclosed |