Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2436534 | 0.91 | L3MBTL1 (0.65) | L3MBTL1TP53SMN1; SMN2AKR1C3MEN1 | |
| SCHEMBL8569015 | 0.89 | CA1 (0.55) | ESR1ESR2TP53SMN1; SMN2CYP3A4 | |
| SCHEMBL521860 | 0.86 | AKR1C3 (0.68) | L3MBTL1TP53SMN1; SMN2AKR1C3MEN1 | |
| Methyl 3-Hydroxybenzoate SCHEMBL29410714 | 0.86 | P4HB (0.67) | ESR1ESR2P4HBNPC1ALDH1A1 | |
| Methyl 3-Hydroxybenzoate SCHEMBL67203 | 0.86 | P4HB (0.67) | ESR1ESR2P4HBNPC1ALDH1A1 | |
| SCHEMBL5558318 | 0.85 | SMN1; SMN2 (0.66) | ESR1ESR2L3MBTL1TP53SMN1; SMN2 | |
| SCHEMBL25620305 | 0.85 | MEN1 (0.59) | L3MBTL1TP53SMN1; SMN2AKR1C3MEN1 | |
| SCHEMBL883130 | 0.85 | TNKS (0.60) | L3MBTL1TP53SMN1; SMN2AKR1C3MEN1 | |
| Methyl 3-Hydroxybenzoate SCHEMBL29071792 | 0.84 | P4HB (0.65) | ESR1ESR2P4HBNPC1ALDH1A1 | |
| SCHEMBL2195918 | 0.83 | L3MBTL1 (0.51) | ESR1ESR2L3MBTL1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-10-21 | — | — | US | disclosed |
| EP-1661879-A1 | DIPHENYL ETHER COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267778-A1 | Diphenyl ether compound, process for producing the same, and use | PPARG, PPARD, PPARA | ESR1 235/4885ESR2 224/4885L3MBTL1 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.