Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 3/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210413 | 0.94 | ALDH1A1 (0.50) | ALDH1A1RECQLKCNA3FFAR4LTA4H | |
| SCHEMBL10960140 | 0.89 | ALDH1A1 (0.63) | ALDH1A1RECQLFFAR4LTA4HRIPK1 | |
| SCHEMBL30292268 | 0.84 | ALDH1A1 (0.56) | ALDH1A1RECQLHSD17B10JAK2LMNA | |
| SCHEMBL30292306 | 0.84 | ALDH1A1 (0.56) | ALDH1A1RECQLHSD17B10JAK2LMNA | |
| SCHEMBL29206247 | 0.84 | ALDH1A1 (0.56) | ALDH1A1RECQLHSD17B10JAK2LMNA | |
| SCHEMBL11727531 | 0.81 | KCNA3 (0.48) | ALDH1A1KCNA3FFAR4LTA4HRIPK1 | |
| SCHEMBL276735 | 0.81 | LTA4H (0.68) | ALDH1A1KCNA3LTA4HLMNAMAPT | |
| SCHEMBL11727969 | 0.81 | KDM4E (0.53) | KCNA3LTA4HHRH1 | |
| SCHEMBL28859173 | 0.81 | KCNA3 (0.48) | ALDH1A1KCNA3FFAR4LTA4HRIPK1 | |
| SCHEMBL10437664 | 0.81 | KCNA3 (0.46) | ALDH1A1KCNA3FFAR4LTA4HRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |