SCHEMBL8955724

SCHEMBL8955724

C/C=C/C1OCC(c2ccc(-c3ccc(-c4ccc(OCC)c(F)c4F)cc3)cc2F)CO1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 7/20 0.35
NAAA Q02083 1/20 0.33
FGFR2 P21802 2/20 0.32
FGFR1 P11362 1/20 0.32
KDM1A O60341 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8955919 0.93 FPR2 (0.36) FPR2
SCHEMBL8955914 0.92 FPR2 (0.32) FPR2
SCHEMBL12999653 0.92 FPR2 (0.30) FPR2
SCHEMBL8955804 0.92 FPR2 (0.35) FPR2
SCHEMBL8955717 0.91 FPR2 (0.35) FPR2
SCHEMBL8955802 0.91 FPR2 (0.35) FPR2
SCHEMBL8955860 0.91 FPR2 (0.35) FPR2
SCHEMBL8955818 0.91 FPR2 (0.35) FPR2
SCHEMBL8957735 0.91 FPR2 (0.37) FPR2FGFR2FGFR1
SCHEMBL8955920 0.91 HTR2C (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed