Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953968 | 0.90 | MAOB (0.42) | TSHRMAOBMAOACYP19A1TP53 | |
| SCHEMBL1305366 | 0.83 | CYP3A4 (0.46) | TSHRMAOBMAOACYP19A1TP53 | |
| SCHEMBL17937737 | 0.81 | KMT2A (0.42) | MAOBCYP3A4 | |
| SCHEMBL17937741 | 0.81 | CYP1A2 (0.47) | MAOBMAOACYP1A2CYP2C19 | |
| SCHEMBL8954018 | 0.80 | TSHR (0.44) | TSHRCYP3A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL708762 | 0.80 | LTA4H (0.44) | TSHRTP53CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL3914309 | 0.76 | MAOB (0.47) | TSHRMAOBMAOACYP19A1TP53 | |
| SCHEMBL8953993 | 0.75 | MAOB (0.47) | TSHRMAOBMAOACYP19A1TP53 | |
| SCHEMBL2874013 | 0.75 | LTA4H (0.44) | TSHRTP53CYP3A4 | |
| SCHEMBL8953958 | 0.74 | TSHR (0.49) | TSHRTP53CYP3A4CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536584-A | SEMICONDUCTOR INTEGRATED CIRCUIT, TRANSISTOR AND A THIN FILM MULTILEVEL WIRING BOARD USES SURFACE PROTECTIVE COATING OF POLYIMIDE | HITACHI, LTD. (JP) | 1996-07-16 | — | — | US | disclosed |
| US-5272247-A | Polyimide precursor, cured product thereof, and processes for producing them | HITACHI, LTD. (JP) | 1993-12-21 | — | — | US | disclosed |