SCHEMBL708762

SCHEMBL708762

CCCCO[SiH](Cc1ccccc1)OCCCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.44
ALDH1A1 P00352 3/20 0.41
TSHR P16473 3/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
HPGD P15428 2/20 0.41
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
TP53 P04637 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SIGMAR1 Q99720 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.37
GLA P06280 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2874013 0.94 LTA4H (0.44) LTA4HALDH1A1TSHRCYP3A4MAPK1
SCHEMBL28994602 0.91 LTA4H (0.41) LTA4HALDH1A1TSHRL3MBTL1TDP1
SCHEMBL703150 0.88 TP53 (0.41) LTA4HALDH1A1TSHRL3MBTL1TDP1
SCHEMBL19809260 0.86 LTA4H (0.41) LTA4HALDH1A1TSHRCYP3A4MAPK1
SCHEMBL15302051 0.85 LTA4H (0.44) LTA4HALDH1A1TSHRL3MBTL1TDP1
SCHEMBL19809422 0.83 TP53 (0.37) LTA4HALDH1A1TSHRL3MBTL1TDP1
SCHEMBL17937686 0.81 SMN1; SMN2 (0.42) ALDH1A1TSHRTDP1HPGDSMN1; SMN2
SCHEMBL17937637 0.81 CYP1A2 (0.41) ALDH1A1L3MBTL1TDP1CYP3A4MAPK1
SCHEMBL8954018 0.81 TSHR (0.44) ALDH1A1TSHRTDP1CYP3A4CYP1A2
SCHEMBL706388 0.81 SIGMAR1 (0.43) LTA4HALDH1A1TSHRL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2107951-A1 COMPOSITION AND METHOD FOR RESTORING AN ELECTRICAL CABLE AND INHIBITING CORROSION IN THE ALUMINUM CONDUCTOR CORE UTILX CORPORATION (US) 2009-10-14 EP claimed
WO-2008088618-A1 COMPOSITION AND METHOD FOR RESTORING AN ELECTRICAL CABLE AND INHIBITING CORROSION IN THE ALUMINUM CONDUCTOR CORE UTILX CORPORATION (US) 2008-07-24 WO claimed
US-20080169450-A1 COMPOSITION AND METHOD FOR RESTORING AN ELECTRICAL CABLE AND INHIBITING CORROSION IN THE ALUMINUM CONDUCTOR CORE UTILX CORPORATION (US) 2008-07-17 US claimed
US-4207424-A ALUMINA PRETREATED WITH SILYLATING AGENT AT ELEVATED TEMPERAUTRE HALCON RESEARCH & DEVELOPMENT CORPORATION (US) 1980-06-10 US claimed
CN-103130825-B The manufacture method of 1,3 difluoro disiloxane compounds 株式会社艾迪科 2016-12-21 CN disclosed
EP-1118385-B1 METHOD FOR PRODUCING HIGH-PERFORMANCE MATERIAL HAVING PHOTOCATALYTIC FUNCTION AND DEVICE THEREFOR TOTO LTD (JP) 2015-01-21 EP disclosed
US-8791221-B2 Addition-curable metallosiloxane compound DAICEL CORPORATION (JP) 2014-07-29 US disclosed
EP-2650319-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND Daicel Corporation (JP) 2013-10-16 EP disclosed
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND DAICEL CORPORATION (JP) 2013-10-10 US disclosed
CN-103249762-A Addition-curable metallosiloxane compound DAICEL CORP 2013-08-14 CN disclosed
EP-2128214-B1 Antifouling member and antifouling coating composition TOTO LTD (JP) 2013-03-20 EP disclosed
US-8124239-B2 Silica film forming material, silica film and method of manufacturing the same, multilayer wiring structure and method of manufacturing the same, and semiconductor device and method of manufacturing the same FUJITSU LIMITED (JP) 2012-02-28 US disclosed
EP-1101803-A1 UNDERCOATING AGENT FOR FORMING PHOTOEXITING COATING FILM OR PHOTOCATALYTIC AND HYDROPHILIC COATING FILM TOTO LTD. (JP) 2001-05-23 EP disclosed
US-6165256-A Photocatalytically hydrophilifiable coating composition TOTO LTD. (JP) 2000-12-26 US disclosed
WO-2000058095-A1 DIRECT DRAWING PLANOGRAPHIC PRINTING PLATE AND PREPARATION METHOD THEREFOR KODAK POLYCHROME GRAPHICS COMPANY LTD. (US) 2000-10-05 WO disclosed
EP-0987317-A1 METHOD FOR SURFACE PRETREATMENT BEFORE FORMATION OF PHOTOCATALYTIC HYDROPHILIC FILM, AND DETERGENT AND UNDERCOAT COMPOSITION FOR USE IN THE SAME TOTO LTD. (JP) 2000-03-22 EP disclosed
US-5939194-A SEMICONDUCTORS; PHOTOEXCITATION TOTO LTD. (JP) 1999-08-17 US disclosed
EP-0913447-A1 PHOTOCATALYTIC HYDROPHILIC COATING COMPOSITION TOTO LTD. (JP) 1999-05-06 EP disclosed
EP-0903389-A1 ANTIFOULING MEMBER AND ANTIFOULING COATING COMPOSITION TOTO LTD. (JP) 1999-03-24 EP disclosed
US-4207424-A ALUMINA PRETREATED WITH SILYLATING AGENT AT ELEVATED TEMPERAUTRE HALCON RESEARCH & DEVELOPMENT CORPORATION (US) 1980-06-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND B2M, MSI2, MNS1 LTA4H 3533/4885ALDH1A1 2073/4885TSHR 4702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.