Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8955891 | 1.00 | SLC6A19 (0.48) | SLC6A19HSD17B3ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL8499687 | 0.93 | CYP1A2 (0.48) | SLC6A19HSD17B3ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL10651535 | 0.93 | CYP1A2 (0.48) | SLC6A19HSD17B3ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL10651538 | 0.93 | CYP1A2 (0.48) | SLC6A19HSD17B3ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL8499685 | 0.93 | CYP1A2 (0.48) | SLC6A19HSD17B3ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL1419505 | 0.83 | HSD17B3 (0.46) | SLC6A19HSD17B3ALDH1A1CYP2D6CHRNA7 | |
| SCHEMBL256054 | 0.82 | SLC6A19 (0.53) | SLC6A19HSD17B3ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL14416285 | 0.82 | SLC6A19 (0.53) | SLC6A19HSD17B3ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL4364007 | 0.82 | SLC6A19 (0.53) | SLC6A19HSD17B3ALDH1A1CYP2D6CYP1A2 | |
| SCHEMBL106151 | 0.81 | PTGS1 (0.46) | LMNAHTTMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516767-A | PRODRUG AS HYPOGLYCEMIC AGENT | SANDOZ LTD. (CH) | 1996-05-14 | — | — | US | disclosed |
| US-5412137-A | Hypoglycemic agents | SANDOZ LTD. (CH) | 1995-05-02 | — | — | US | disclosed |