SCHEMBL8956206

SCHEMBL8956206

O=S(=O)(Cc1ccccc1)Nc1cccc(O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.55
AR P10275 1/20 0.55
HPGD P15428 1/20 0.54
PGR P06401 1/20 0.53
CYP19A1 P11511 1/20 0.52
BRD4 O60885 2/20 0.52
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
MMP1 P03956 1/20 0.51
MMP2 P08253 1/20 0.51
MMP9 P14780 1/20 0.51
MMP8 P22894 1/20 0.51
MMP13 P45452 1/20 0.51
NPC1 O15118 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HDAC1 Q13547 2/20 0.49
ALOX15 P16050 1/20 0.49
HSD17B10 Q99714 1/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL633995 0.82 KMT2A (0.76) KMT2AARHPGDPGRCYP19A1
Formic Acid SCHEMBL28188423 0.82 HSD17B2 (0.57) ARBRD4NPC1ALDH1A1HDAC1
SCHEMBL6567551 0.81 KMT2A (0.70) KMT2AARHPGDPGRCYP19A1
SCHEMBL6797222 0.81 HPGD (0.58) KMT2AHPGDPGRNPC1ALDH1A1
SCHEMBL9478969 0.81 KMT2A (0.59) KMT2AARHPGDPGRCYP19A1
SCHEMBL2725642 0.81 HTR6 (0.59) KMT2AARHPGDPGRCYP19A1
SCHEMBL359651 0.81 KMT2A (0.69) KMT2AARHPGDPGRCYP19A1
Formic Acid SCHEMBL28188578 0.81 HSD17B2 (0.49) ARBRD4NPC1ALDH1A1HDAC1
SCHEMBL11126460 0.80 HSD17B2 (0.55) HPGDBRD4ALDH1A1
SCHEMBL15474246 0.78 PGR (0.75) KMT2AARHPGDPGRCYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0360014-B1 Photosensitive material and image forming method using same CANON KK (JP) 1996-01-03 EP disclosed
US-5415974-A Silver halide, organic silver salt, polymerizable compound, heat-diffusing dye CANON KABUSHIKI KAISHA (JP) 1995-05-16 US disclosed