Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | MIF | P14174 | 1/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 2/20 | 0.40 |
| ▸ | RARB | P10826 | 2/20 | 0.40 |
| ▸ | RARG | P13631 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3864856 | 0.84 | ALDH1A1 (0.50) | ALDH1A1LMNAALOX15NR1I2CYP2C9 | |
| SCHEMBL75568 | 0.83 | APEX1 (0.49) | ALDH1A1ALOX15HSD17B10GAAPTGDR2 | |
| SCHEMBL6773355 | 0.83 | ELANE (0.49) | ALDH1A1LMNAALOX15NR1I2CYP2C9 | |
| SCHEMBL15422590 | 0.83 | NR1H4 (0.42) | ALDH1A1LMNAALOX15GAAPTGDR2 | |
| SCHEMBL28531330 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAALOX15NR1I2CYP2C9 | |
| SCHEMBL18940924 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNAALOX15NR1I2CYP2C9 | |
| SCHEMBL29185985 | 0.81 | KDM4E (0.55) | ALDH1A1LMNAHTTGAAPTGDR2 | |
| SCHEMBL29021762 | 0.81 | RBP4 (0.47) | ALDH1A1LMNAGAAPTGDR2RARA | |
| SCHEMBL29556483 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAALOX15NR1I2CYP2C9 | |
| SCHEMBL11807412 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAALOX15NR1I2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060018-A | N, N-diaryl urea derivative and application thereof | 杭州百新生物医药科技有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-118613288-A | Immunoconjugates comprising kallikrein-related peptidase 2 antigen binding domains and uses thereof | 詹森生物科技公司 | 2024-09-06 | — | — | CN | disclosed |
| CN-118302204-A | Macrocyclic compounds and diagnostic uses thereof | 詹森生物科技公司 | 2024-07-05 | — | — | CN | disclosed |
| EP-0374513-B1 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5231091-A | Antihistamines, anaphylactic, respiratory system disorders, cardiovascular disorders ans septic shock | AMERICAN CYANAMID COMPANY (US) | 1993-07-27 | — | — | US | disclosed |
| US-5147864-A | Bronchodilator agent, antianaphylactic agent, antishock agent, cardiotonic agent and anticarcinogenic agent | AMERICAN CYANAMID COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| US-4983592-A | Bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID CO. (US) | 1991-01-08 | — | — | US | disclosed |
| EP-0374513-A2 | Novel bis-arylphosphate ester antagonists of platelet activating factor | AMERICAN CYANAMID COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |