Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.45 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8956643 | 0.93 | USP2 (0.38) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL8956632 | 0.85 | USP2 (0.40) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL10304548 | 0.84 | EPHX1 (0.53) | MMP8EPHX1RRM1DPP7GNAI3 | |
| SCHEMBL27577203 | 0.84 | EPHX1 (0.53) | MMP8EPHX1RRM1DPP7GNAI3 | |
| SCHEMBL929877 | 0.79 | ALDH1A1 (0.48) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL9124672 | 0.78 | ALDH1A2 (0.45) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL929789 | 0.77 | ALDH1A1 (0.50) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL8956719 | 0.76 | MEN1 (0.51) | USP2TSHR | |
| SCHEMBL929767 | 0.76 | ALDH1A2 (0.42) | HDAC1HDAC2HDAC10HDAC8HDAC6 | |
| SCHEMBL4577660 | 0.75 | KMT2A (0.52) | ALDH1A2ALDH1A1ALDH2ALDH1A3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514282-B1 | Alkylamino mercaptoalkylamides or salts thereof acceptable for cosmetic use, their use as a reducing agent and a process for the permanent deformation of hair | OREAL (FR) | 1996-04-10 | — | — | EP | claimed |
| US-5583257-A | REDUCING AGENTS FOR PERMANENT HAIR; ODORLESS | L'OREAL (FR) | 1996-12-10 | — | — | US | disclosed |
| US-5449805-A | Permanent waves for hair | L'OREAL (FR) | 1995-09-12 | — | — | US | disclosed |
| US-5334377-A | Reduction of the disulfide bond of keratin; the oxidation | L'OREAL (FR) | 1994-08-02 | — | — | US | disclosed |