Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864534 | 0.95 | MAPT (0.61) | MAPTALDH1A1LMNACYP3A4HSD17B10 | |
| SCHEMBL5373240 | 0.90 | MAPT (0.59) | MAPTALDH1A1LMNACYP3A4HSD17B10 | |
| SCHEMBL8956968 | 0.90 | MAPT (0.59) | MAPTALDH1A1LMNACYP3A4HSD17B10 | |
| SCHEMBL28411160 | 0.89 | MAPT (0.58) | MAPTALDH1A1LMNACYP3A4HSD17B10 | |
| SCHEMBL9340880 | 0.89 | ESR1 (0.55) | MAPTALDH1A1LMNACYP3A4HSD17B10 | |
| SCHEMBL9340873 | 0.89 | ESR1 (0.55) | MAPTALDH1A1LMNACYP3A4HSD17B10 | |
| SCHEMBL28875159 | 0.88 | MAPT (0.56) | MAPTALDH1A1LMNACYP3A4HSD17B10 | |
| SCHEMBL26185708 | 0.85 | MAPT (0.65) | MAPTALDH1A1LMNACYP3A4HSD17B10 | |
| SCHEMBL8956949 | 0.84 | LMNA (0.53) | MAPTALDH1A1LMNACYP3A4HSD17B10 | |
| SCHEMBL9493539 | 0.83 | MAPT (0.78) | MAPTALDH1A1LMNACYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486310-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1996-01-23 | — | — | US | disclosed |
| EP-0339414-B1 | Optically active diester | HOFFMANN LA ROCHE (CH) | 1993-12-01 | — | — | EP | disclosed |
| US-5242619-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1993-09-07 | — | — | US | disclosed |