SCHEMBL8957146

SCHEMBL8957146

CCCCCC1OCC(c2ccc(-c3ccc(-c4ccc(OC)c(F)c4F)cc3)c(F)c2F)CO1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 18/20 0.39
LYPLA1 O75608 1/20 0.31
LYPLA2 O95372 1/20 0.31
ABHD16A O95870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8957282 0.99 FPR2 (0.38) FPR2LYPLA1LYPLA2ABHD16A
SCHEMBL8956870 0.92 FPR2 (0.40) FPR2
SCHEMBL8957071 0.91 FPR2 (0.37) FPR2
SCHEMBL8954910 0.91 FPR2 (0.36) FPR2
SCHEMBL8957301 0.90 FPR2 (0.36) FPR2
SCHEMBL8957239 0.90 FPR2 (0.37) FPR2
SCHEMBL8957160 0.90 FPR2 (0.35) FPR2
SCHEMBL8955052 0.90 FPR2 (0.35) FPR2LYPLA1LYPLA2ABHD16A
SCHEMBL8957200 0.89 FPR2 (0.37) FPR2
SCHEMBL8957325 0.89 FPR2 (0.37) FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed