SCHEMBL8957282

SCHEMBL8957282

CCCCCCCC1OCC(c2ccc(-c3ccc(-c4ccc(OC)c(F)c4F)cc3)c(F)c2F)CO1

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 14/20 0.38
LYPLA1 O75608 1/20 0.33
LYPLA2 O95372 1/20 0.33
ABHD16A O95870 1/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8957146 0.99 FPR2 (0.39) FPR2LYPLA1LYPLA2ABHD16A
SCHEMBL8957301 0.92 FPR2 (0.36) FPR2ALDH1A1
SCHEMBL8956870 0.91 FPR2 (0.40) FPR2
SCHEMBL8955052 0.91 FPR2 (0.35) FPR2LYPLA1LYPLA2ABHD16ACYP3A4
SCHEMBL8957219 0.91 FPR2 (0.37) FPR2ALDH1A1TDP1
SCHEMBL8957380 0.91 FPR2 (0.37) FPR2ALDH1A1TDP1
SCHEMBL8957325 0.91 FPR2 (0.37) FPR2ALDH1A1TDP1
SCHEMBL8957200 0.91 FPR2 (0.37) FPR2ALDH1A1TDP1
SCHEMBL8957304 0.91 FPR2 (0.35) FPR2ALDH1A1
SCHEMBL8957318 0.91 FPR2 (0.37) FPR2ALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
US-20100309402-A1 FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE CHISSO CORPORATION (JP) 2010-12-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100309402-A1 FOUR- OR FIVE-RING LIQUID CRYSTAL COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE KIF23, HCN3, FZD7 FPR2 1427/4885LYPLA1 3903/4885LYPLA2 3471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.