Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 7/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2287185 | 0.94 | ATM (0.53) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL28755162 | 0.94 | ATM (0.53) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL2293325 | 0.94 | ATM (0.53) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL28714996 | 0.94 | ATM (0.53) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL2293709 | 0.93 | L3MBTL1 (0.54) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL2294906 | 0.89 | L3MBTL1 (0.59) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL29163411 | 0.89 | ZDHHC2 (0.49) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL3929624 | 0.89 | ZDHHC2 (0.49) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL11296486 | 0.89 | ZDHHC2 (0.49) | GAAXBP1ATMNPSR1L3MBTL1 | |
| SCHEMBL8208789 | 0.87 | L3MBTL1 (0.58) | GAAXBP1ATMNPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5512565-A | REDUCE CHOLESTEROL ABSORPTION IN MAMMALS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-04-30 | — | — | US | disclosed |