Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8957714 | 0.93 | THRB (0.33) | THRBTSHR | |
| SCHEMBL8957663 | 0.92 | ALDH1A1 (0.36) | THRB | |
| SCHEMBL8957687 | 0.89 | ALDH1A1 (0.35) | THRB | |
| SCHEMBL8957698 | 0.86 | ALDH1A1 (0.36) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL8957764 | 0.85 | CYP2C19 (0.38) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL9067395 | 0.83 | THRB (0.38) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL8957604 | 0.82 | THRB (0.41) | THRBTSHRPOLBAPEX1HTT | |
| SCHEMBL8957603 | 0.82 | — | — | |
| SCHEMBL8957726 | 0.81 | ALDH1A1 (0.34) | THRBTSHRTDP1 | |
| SCHEMBL8957727 | 0.80 | CYP2C19 (0.36) | THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556931-A | LENSES | TOKUYAMA CORPORATION (JP) | 1996-09-17 | — | — | US | disclosed |
| EP-0691550-A2 | Polymerizable composition and organic glass | TOKUYAMA CORPORATION (JP) | 1996-01-10 | — | — | EP | disclosed |