SCHEMBL8957740

SCHEMBL8957740

CCCOc1ccccc1N[C]=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.52
MEN1 O00255 3/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
MAPT P10636 4/20 0.50
GAA P10253 2/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 2/20 0.50
PKM P14618 1/20 0.50
HTT P42858 1/20 0.50
NLRP1 Q9C000 1/20 0.50
MRGPRX1 Q96LB2 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TSHR P16473 2/20 0.42
POLB P06746 1/20 0.42
NPSR1 Q6W5P4 2/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NR3C1 P04150 1/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL226502 0.92 KMT2A (0.54) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL10389740 0.90 KMT2A (0.49) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL6769635 0.89 KMT2A (0.50) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL2201550 0.89 KMT2A (0.50) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL5361999 0.86 GAA (0.56) KMT2AMEN1NPC1MAPTGAA
SCHEMBL13477751 0.78 KMT2A (0.54) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL4639366 0.77 NPC1 (0.56) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL27778851 0.77 KMT2A (0.53) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL18415529 0.76 NPC1 (0.68) KMT2AMEN1NPC1RAB9AMAPT
SCHEMBL2444691 0.76 BRD4 (0.58) MAPTALDH1A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0313083-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1996-01-10 EP disclosed
US-H1248-H SUPERIOR DESILVERING SPEED, GOOD COLOR REFORMING PROPERTIES AND MINIMUM IMAGE DENSITIES FUJI PHOTO FILM CO., LTD. (JP) 1993-11-02 US disclosed
EP-0295632-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1993-03-03 EP disclosed
US-5112729-A Cyan coupler and an ultraviolet radiation absorber FUJI PHOTO FILM CO., LTD. (JP) 1992-05-12 US disclosed
US-5064750-A Naphthol amido coupler, bleaching bath of diamino propane teraacetato iron complex FUJI PHOTO FILM CO., LTD. (JP) 1991-11-12 US disclosed
EP-0301477-B1 SILVER HALIDE COLOR PHOTOSENSITIVE MATERIAL AND METHOD OF PROCESSING THEREOF Fuji Photo Film Co., Ltd. (JP) 1991-04-03 EP disclosed
EP-0313083-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1989-04-26 EP disclosed
EP-0307927-A2 Silver halide color photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1989-03-22 EP disclosed
EP-0301477-A2 Silver halide color photosensitive material and method of processing thereof Fuji Photo Film Co., Ltd. (JP) 1989-02-01 EP disclosed
EP-0295632-A2 Silver halide color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-12-21 EP disclosed