Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18462548 | 0.96 | ALDH1A1 (0.43) | ALDH1A1MAPK1MEN1KMT2AHIF1A | |
| SCHEMBL22858756 | 0.89 | HRH4 (0.36) | ALDH1A1MEN1KMT2AHIF1AHRH4 | |
| SCHEMBL9178197 | 0.81 | HRH4 (0.38) | MEN1KMT2AHRH4 | |
| SCHEMBL22487790 | 0.77 | ADORA1 (0.38) | HRH4 | |
| SCHEMBL9844062 | 0.77 | HPGD (0.56) | ALDH1A1MEN1KMT2AHIF1APARP1 | |
| SCHEMBL9843755 | 0.73 | HPGD (0.59) | ALDH1A1MEN1KMT2AHIF1APARP1 | |
| SCHEMBL13318361 | 0.73 | HRH4 (0.35) | HRH4 | |
| SCHEMBL24549747 | 0.72 | TNKS2 (0.39) | KMT2AHRH4 | |
| SCHEMBL1082422 | 0.72 | HPGD (0.55) | ALDH1A1MEN1KMT2AHIF1APARP1 | |
| Hydrochloric Acid SCHEMBL14716148 | 0.72 | HDAC6 (0.36) | HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559233-A | 3-/P-PHENYLBENZYL/IMIDAZOLONES AND PYRIMIDONES | SANOFI (FR) | 1996-09-24 | — | — | US | disclosed |
| US-5352788-A | Angiotensin antagonist | ELF SANOFI (FR) | 1994-10-04 | — | — | US | disclosed |
| US-5270317-A | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-14 | — | — | US | disclosed |