Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | ICMT | O60725 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL8957910 | 0.99 | RAB9A (0.43) | RAB9ANPC1JAK2PAX8ICMT | |
| Potassium SCHEMBL8958398 | 0.99 | RAB9A (0.43) | RAB9ANPC1JAK2PAX8ICMT | |
| Potassium SCHEMBL8958150 | 0.99 | RAB9A (0.43) | RAB9ANPC1JAK2PAX8ICMT | |
| Potassium SCHEMBL8958227 | 0.99 | RAB9A (0.43) | RAB9ANPC1JAK2PAX8ICMT | |
| Potassium SCHEMBL8957908 | 0.93 | ESR2 (0.39) | RAB9ATSHRLMNADRD2OPRM1 | |
| SCHEMBL8958019 | 0.81 | CHRM2 (0.42) | RAB9AALDH1A1TSHRLMNADRD2 | |
| SCHEMBL235012 | 0.71 | NPC1 (0.47) | RAB9ANPC1JAK2PAX8ICMT | |
| SCHEMBL233200 | 0.71 | NPC1 (0.47) | RAB9ANPC1JAK2PAX8ICMT | |
| SCHEMBL235953 | 0.71 | NPC1 (0.47) | RAB9ANPC1JAK2PAX8ICMT | |
| SCHEMBL235949 | 0.71 | NPC1 (0.47) | RAB9ANPC1JAK2PAX8ICMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535842-B1 | Benzofuranones | ZENECA LTD (GB) | 1996-01-10 | — | — | EP | disclosed |
| US-5389597-A | For dye diffusion thermal transfer printing | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-02-14 | — | — | US | disclosed |
| US-5268490-A | With indan-1,3-dione and aminobenzene ring | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-07 | — | — | US | disclosed |
| EP-0535842-A1 | Benzofuranones | ZENECA LIMITED (GB) | 1993-04-07 | — | — | EP | disclosed |