Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL8957908 | 0.82 | ESR2 (0.39) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL8958183 | 0.81 | RAB9A (0.43) | CYP1A2CYP2D6CYP2C19TSHRLMNA | |
| Potassium SCHEMBL8958150 | 0.80 | RAB9A (0.43) | CYP1A2CYP2D6CYP2C19TSHRLMNA | |
| Potassium SCHEMBL8958227 | 0.80 | RAB9A (0.43) | CYP1A2CYP2D6CYP2C19TSHRLMNA | |
| Potassium SCHEMBL8958398 | 0.80 | RAB9A (0.43) | CYP1A2CYP2D6CYP2C19TSHRLMNA | |
| Potassium SCHEMBL8957910 | 0.80 | RAB9A (0.43) | CYP1A2CYP2D6CYP2C19TSHRLMNA | |
| SCHEMBL3487783 | 0.75 | KIF11 (0.41) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL5130509 | 0.72 | KCNN4 (0.52) | MAPTKMT2ACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL3947548 | 0.68 | MAPT (0.53) | CHRM2CHRM1CHRM3MAPTKMT2A | |
| SCHEMBL31384465 | 0.68 | ALDH1A1 (0.42) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535842-B1 | Benzofuranones | ZENECA LTD (GB) | 1996-01-10 | — | — | EP | disclosed |
| US-5389597-A | For dye diffusion thermal transfer printing | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-02-14 | — | — | US | disclosed |
| US-5268490-A | With indan-1,3-dione and aminobenzene ring | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-12-07 | — | — | US | disclosed |
| EP-0535842-A1 | Benzofuranones | ZENECA LIMITED (GB) | 1993-04-07 | — | — | EP | disclosed |