Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.47 |
| ▸ | HTR3B | O95264 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958198 | 1.00 | RAB9A (0.50) | RAB9ANPC1MEN1KMT2ACA12 | |
| SCHEMBL1405603 | 0.83 | CA1 (0.65) | RAB9ANPC1MEN1KMT2ACA12 | |
| SCHEMBL1405602 | 0.83 | CA1 (0.65) | RAB9ANPC1MEN1KMT2ACA12 | |
| SCHEMBL22062151 | 0.81 | NPC1 (0.71) | RAB9ANPC1MEN1KMT2ACA12 | |
| SCHEMBL17273888 | 0.76 | CA1 (0.55) | RAB9ANPC1MEN1KMT2ACA12 | |
| SCHEMBL12589442 | 0.76 | CA1 (0.55) | RAB9ANPC1MEN1KMT2ACA12 | |
| SCHEMBL14583510 | 0.76 | CA1 (0.55) | RAB9ANPC1MEN1KMT2ACA12 | |
| SCHEMBL21242229 | 0.76 | KMT2A (0.57) | RAB9ANPC1MEN1KMT2ACA12 | |
| SCHEMBL1405136 | 0.74 | CA4 (0.59) | RAB9ANPC1MEN1KMT2ACA12 | |
| SCHEMBL10001954 | 0.74 | CA1 (0.52) | RAB9ANPC1MEN1KMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523436-A | ARYL-ALKYL TRIAZENIDO TRANSITION METAL COMPLEXES; HIGH ACTIVATION ENERGY; CROSSLINKED POLYSILOXANES | WACKER-CHEMIE GMBH (DE) | 1996-06-04 | — | — | US | disclosed |
| EP-0602638-B1 | Catalysts for hydrosilylation reactions | WACKER CHEMIE GMBH (DE) | 1996-03-06 | — | — | EP | disclosed |
| EP-0636642-B1 | Transition metal complexes bound to organopolysiloxanes | WACKER CHEMIE GMBH (DE) | 1995-12-06 | — | — | EP | disclosed |
| EP-0636642-A1 | Transition metal complexes bound to organopolysiloxanes | Wacker-Chemie GmbH (DE) | 1995-02-01 | — | — | EP | disclosed |
| EP-0602638-A1 | Catalysts for hydrosilylation reactions | Wacker-Chemie GmbH (DE) | 1994-06-22 | — | — | EP | disclosed |