Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ING2 | Q9H160 | 3/20 | 0.59 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.37 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31323237 | 0.78 | DUSP5 (0.58) | ING2DUSP5DUSP6CA1CA2 | |
| SCHEMBL18863517 | 0.77 | ING2 (0.50) | ING2CA1CA2CA12CA7 | |
| SCHEMBL11802845 | 0.75 | TDP1 (0.54) | ING2CA1CA2CA12CYP3A4 | |
| SCHEMBL16308957 | 0.75 | ALDH1A1 (0.42) | ING2MAPTLCKFYNALDH1A1 | |
| SCHEMBL2217165 | 0.75 | CYP3A4 (0.52) | CA1CA2CA12CYP3A4MAPT | |
| SCHEMBL29664959 | 0.74 | ING2 (1.00) | ING2DUSP5DUSP6CA1CA2 | |
| SCHEMBL19203101 | 0.74 | ING2 (1.00) | ING2DUSP5DUSP6CA1CA2 | |
| SCHEMBL29486957 | 0.74 | ING2 (1.00) | ING2DUSP5DUSP6CA1CA2 | |
| SCHEMBL29776588 | 0.74 | ING2 (1.00) | ING2DUSP5DUSP6CA1CA2 | |
| SCHEMBL29486958 | 0.74 | ING2 (1.00) | ING2DUSP5DUSP6CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489612-A | CONTAINING AN ACIDIC GROUP SUCH AS A SULFONATE OR CARBOXY GROUP AND A HYDROXY OR ETHER SUBSTITUENT; RESPIRATORY, CARDIOVASCULAR AND GASTROINTESTINAL DISORDERS | THE UNIVERSITY OF ALABAMA AT BIRMINGHAM RESEARCH FOUNDATION (US) | 1996-02-06 | — | — | US | disclosed |