(Phenylsulfonyl)Benzene

(Phenylsulfonyl)Benzene

SCHEMBL8958296

NC(=O)O.O=S(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.74
CA1 P00915 3/20 0.52
CA2 P00918 3/20 0.52
CA12 O43570 2/20 0.52
CA7 P43166 2/20 0.52
CA13 Q8N1Q1 2/20 0.52
CA3 P07451 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA5A P35218 1/20 0.52
PLA2G7 Q13093 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
CA5B Q9Y2D0 1/20 0.52
TSHR P16473 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
HPGD P15428 2/20 0.50
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Phenylsulfonyl)Benzene SCHEMBL28297601 0.95 HTR6 (0.74) HTR6CA1CA2CA12CA7
(Phenylsulfonyl)Benzene SCHEMBL7774155 0.89 HTR6 (0.82) HTR6CA1CA2CA12CA7
(Phenylsulfonyl)Benzene SCHEMBL28237512 0.89 HTR6 (0.93) HTR6CA1CA2CA12CA7
(Phenylsulfonyl)Benzene SCHEMBL9642349 0.86 HTR6 (0.78) HTR6CA1CA2CA12CA7
(Phenylsulfonyl)Benzene SCHEMBL1736247 0.86 MAPT (0.62) HTR6CA1CA2CA12CA9
(Phenylsulfonyl)Benzene SCHEMBL27434463 0.86 HTR6 (0.61) HTR6CA1CA2CA12CA7
(Phenylsulfonyl)Benzene SCHEMBL27791085 0.86 HTR6 (0.88) HTR6CA1CA2CA12CA7
(Phenylsulfonyl)Benzene SCHEMBL29450723 0.86 HTR6 (1.00) HTR6CA1CA2CA12CA7
(Phenylsulfonyl)Benzene SCHEMBL29775288 0.86 HTR6 (1.00) HTR6CA1CA2CA12CA7
(Phenylsulfonyl)Benzene SCHEMBL29473549 0.86 HTR6 (1.00) HTR6CA1CA2CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5500432-A Induction and inhibition of apoptosis THE SCRIPPS RESEARCH INSTITUTE (US) 1996-03-19 US disclosed