Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958421 | 1.00 | MGLL (0.50) | MGLLMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3342373 | 0.82 | MAPT (0.54) | MGLLMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10877789 | 0.82 | MAPT (0.54) | MGLLMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10877793 | 0.82 | MAPT (0.54) | MGLLMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3342369 | 0.82 | MAPT (0.54) | MGLLMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3427340 | 0.79 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10428051 | 0.77 | NAAA (0.44) | ALDH1A1HTT | |
| SCHEMBL8958323 | 0.77 | NAAA (0.44) | ALDH1A1HTT | |
| SCHEMBL10428049 | 0.77 | NAAA (0.44) | ALDH1A1HTT | |
| SCHEMBL15485856 | 0.77 | KCNH2 (0.66) | MAPTALDH1A1CHRM2LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523436-A | ARYL-ALKYL TRIAZENIDO TRANSITION METAL COMPLEXES; HIGH ACTIVATION ENERGY; CROSSLINKED POLYSILOXANES | WACKER-CHEMIE GMBH (DE) | 1996-06-04 | — | — | US | disclosed |
| EP-0602638-B1 | Catalysts for hydrosilylation reactions | WACKER CHEMIE GMBH (DE) | 1996-03-06 | — | — | EP | disclosed |
| EP-0636642-B1 | Transition metal complexes bound to organopolysiloxanes | WACKER CHEMIE GMBH (DE) | 1995-12-06 | — | — | EP | disclosed |
| EP-0636642-A1 | Transition metal complexes bound to organopolysiloxanes | Wacker-Chemie GmbH (DE) | 1995-02-01 | — | — | EP | disclosed |
| EP-0602638-A1 | Catalysts for hydrosilylation reactions | Wacker-Chemie GmbH (DE) | 1994-06-22 | — | — | EP | disclosed |