Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.73 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.57 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958449 | 1.00 | ACHE (0.73) | ACHEAGTR1LTB4R2 | |
| SCHEMBL8958445 | 1.00 | ACHE (0.73) | ACHEAGTR1LTB4R2 | |
| SCHEMBL8958325 | 0.90 | ACHE (0.72) | ACHEAGTR1LTB4R2 | |
| SCHEMBL8958320 | 0.90 | ACHE (0.72) | ACHEAGTR1LTB4R2 | |
| SCHEMBL8958315 | 0.90 | ACHE (0.72) | ACHEAGTR1LTB4R2 | |
| SCHEMBL8958308 | 0.88 | ACHE (0.71) | ACHEAGTR1LTB4R2 | |
| SCHEMBL8958312 | 0.88 | ACHE (0.71) | ACHEAGTR1LTB4R2 | |
| SCHEMBL8958301 | 0.88 | ACHE (0.71) | ACHEAGTR1LTB4R2 | |
| SCHEMBL8958442 | 0.86 | ACHE (0.78) | ACHEAGTR1LTB4R2 | |
| Trifluoroacetic Acid SCHEMBL8957969 | 0.86 | AGTR1 (0.66) | AGTR1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559233-A | 3-/P-PHENYLBENZYL/IMIDAZOLONES AND PYRIMIDONES | SANOFI (FR) | 1996-09-24 | — | — | US | disclosed |
| US-5352788-A | Angiotensin antagonist | ELF SANOFI (FR) | 1994-10-04 | — | — | US | disclosed |
| US-5270317-A | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-14 | — | — | US | disclosed |