Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 18/20 | 0.66 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805734 | 0.80 | MTTP (1.00) | MTTP | |
| SCHEMBL6805732 | 0.80 | MTTP (1.00) | MTTP | |
| SCHEMBL29527526 | 0.77 | CTSS (0.73) | F2F10PRSS1 | |
| SCHEMBL9030773 | 0.74 | CHRNB2 (0.45) | — | |
| SCHEMBL841018 | 0.74 | KCNA5 (0.46) | MTTP | |
| SCHEMBL4200553 | 0.74 | CTSS (0.73) | F2F10PRSS1 | |
| SCHEMBL4200549 | 0.74 | CTSS (0.73) | F2F10PRSS1 | |
| SCHEMBL2782748 | 0.74 | CHRNB2 (0.59) | — | |
| SCHEMBL7448308 | 0.74 | HDAC1 (0.52) | F2F10PRSS1 | |
| SCHEMBL6810322 | 0.74 | MTTP (0.73) | MTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559233-A | 3-/P-PHENYLBENZYL/IMIDAZOLONES AND PYRIMIDONES | SANOFI (FR) | 1996-09-24 | — | — | US | disclosed |
| US-5352788-A | Angiotensin antagonist | ELF SANOFI (FR) | 1994-10-04 | — | — | US | disclosed |
| US-5270317-A | N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present | ELF SANOFI (FR) | 1993-12-14 | — | — | US | disclosed |