SCHEMBL8958864

SCHEMBL8958864

CCOC(=O)c1ccc(O)c(NC(C)=O)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.64
CA1 P00915 3/20 0.64
CA2 P00918 3/20 0.64
CA7 P43166 3/20 0.64
CA9 Q16790 3/20 0.64
CA14 Q9ULX7 3/20 0.64
KMT2A Q03164 2/20 0.61
HSD17B2 P37059 1/20 0.57
SMN1; SMN2 Q16637 6/20 0.54
RAB9A P51151 4/20 0.54
NPC1 O15118 3/20 0.54
STAT1 P42224 1/20 0.52
ESR1 P03372 1/20 0.51
ESR2 Q92731 1/20 0.51
ALDH1A1 P00352 3/20 0.50
POLB P06746 3/20 0.49
KDM4E B2RXH2 2/20 0.49
CYP1A2 P05177 1/20 0.48
HPGD P15428 2/20 0.48
MEN1 O00255 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29097191 0.88 KMT2A (0.65) CA12CA1CA2CA7CA9
SCHEMBL31375393 0.88 KMT2A (0.65) CA12CA1CA2CA7CA9
SCHEMBL8080746 0.86 HPGD (0.64) SMN1; SMN2ESR1ALDH1A1POLBKDM4E
SCHEMBL8958854 0.85 KMT2A (0.61) CA12CA1CA2CA7CA9
SCHEMBL7420862 0.84 ALDH1A1 (0.69) CA12CA1CA2CA7CA9
SCHEMBL1459457 0.84 ALDH1A1 (0.73) CA12CA1CA2CA7CA9
SCHEMBL5682954 0.83 KMT2A (0.67) CA12CA1CA2CA7CA9
SCHEMBL2546079 0.82 CYP1A2 (0.63) KMT2ASMN1; SMN2RAB9ANPC1STAT1
SCHEMBL1261218 0.81 KMT2A (0.64) CA12CA1CA2CA7CA9
SCHEMBL21722983 0.81 KMT2A (0.64) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0436938-B1 Silver halide color photographic material containing yellow colored cyan coupler FUJI PHOTO FILM CO LTD (JP) 1996-06-19 EP disclosed
EP-0451526-B1 Silver halide colour photographic materials FUJI PHOTO FILM CO LTD (JP) 1996-01-24 EP disclosed
EP-0451526-A2 Silver halide colour photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1991-10-16 EP disclosed