Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.33 |
| ▸ | CHRNG | P07510 | 2/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | CHRND | Q07001 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | CHIT1 | Q13231 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 4/20 | 0.31 |
| ▸ | DRD3 | P35462 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959082 | 0.78 | MAPK1 (0.39) | TRPA1POLBSSTR1SSTR4CHIT1 | |
| SCHEMBL15120006 | 0.72 | TRPA1 (0.42) | TRPA1SLC6A4SLC6A3SLC6A2SSTR1 | |
| SCHEMBL900000 | 0.72 | TRPA1 (0.42) | TRPA1SLC6A4SLC6A3SLC6A2SSTR1 | |
| SCHEMBL15120005 | 0.72 | TRPA1 (0.42) | TRPA1SLC6A4SLC6A3SLC6A2SSTR1 | |
| SCHEMBL27927268 | 0.72 | TRPA1 (0.42) | TRPA1SLC6A4SLC6A3SLC6A2SSTR1 | |
| SCHEMBL17772302 | 0.66 | TRPA1 (0.39) | TRPA1CHIT1ALDH1A1KCNH2 | |
| SCHEMBL16681946 | 0.64 | TRPA1 (0.42) | TRPA1SLC6A4SLC6A3SLC6A2SSTR1 | |
| SCHEMBL10331964 | 0.64 | TRPA1 (0.42) | TRPA1SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL14981032 | 0.64 | TRPA1 (0.45) | TRPA1SLC6A4SLC6A3SLC6A2SSTR1 | |
| SCHEMBL18609377 | 0.63 | TRPA1 (0.41) | TRPA1SLC6A4SLC6A3CHRNA1CHRNG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474303-B1 | Process for the preparation of cyclopentane derivatives and intermediates therefor | SHELL INT RESEARCH (NL) | 1996-01-17 | — | — | EP | disclosed |
| US-5151550-A | Cyclopentane derivatives | SHELL RESEARCH LIMITED (GB) | 1992-09-29 | — | — | US | disclosed |
| EP-0474303-A1 | Process for the preparation of cyclopentane derivatives and intermediates therefor | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-11 | — | — | EP | disclosed |