Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8958900 | 0.78 | TRPA1 (0.39) | TRPA1CCR2SSTR1SSTR4POLB | |
| SCHEMBL8958970 | 0.74 | TRPA1 (0.40) | MAPK1TRPA1TSHRSSTR1SSTR4 | |
| Bicarbonate SCHEMBL9056056 | 0.65 | TSHR (0.46) | TRPA1CCR2TSHRMEN1KMT2A | |
| SCHEMBL18577408 | 0.64 | CHIT1 (0.43) | MAPK1TRPA1TSHRALDH1A1CHIT1 | |
| SCHEMBL30879620 | 0.64 | TRPA1 (0.41) | MAPK1TRPA1TSHRSSTR1SSTR4 | |
| SCHEMBL25385984 | 0.63 | CHIT1 (0.47) | TRPA1TSHRPOLBCHIT1HPGD | |
| SCHEMBL27995137 | 0.63 | OPRM1 (0.41) | SSTR1SSTR4POLBMEN1KMT2A | |
| SCHEMBL1783397 | 0.63 | TSHR (0.44) | MAPK1TRPA1TSHRPOLBMEN1 | |
| SCHEMBL10331964 | 0.62 | TRPA1 (0.42) | TRPA1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL14981032 | 0.62 | TRPA1 (0.45) | TRPA1SSTR1SSTR4ALDH1A1CHIT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474303-B1 | Process for the preparation of cyclopentane derivatives and intermediates therefor | SHELL INT RESEARCH (NL) | 1996-01-17 | — | — | EP | disclosed |
| US-5151550-A | Cyclopentane derivatives | SHELL RESEARCH LIMITED (GB) | 1992-09-29 | — | — | US | disclosed |
| EP-0474303-A1 | Process for the preparation of cyclopentane derivatives and intermediates therefor | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-11 | — | — | EP | disclosed |