Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | ARG1 | P05089 | 1/20 | 0.37 |
| ▸ | ARG2 | P78540 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14981032 | 0.81 | TRPA1 (0.45) | TRPA1CCR5LMNACHIT1SSTR1 | |
| SCHEMBL15120005 | 0.77 | TRPA1 (0.42) | TRPA1CCR5LMNAMAPK1CHIT1 | |
| SCHEMBL900000 | 0.77 | TRPA1 (0.42) | TRPA1CCR5LMNAMAPK1CHIT1 | |
| SCHEMBL15120006 | 0.77 | TRPA1 (0.42) | TRPA1CCR5LMNAMAPK1CHIT1 | |
| SCHEMBL16681946 | 0.77 | TRPA1 (0.42) | TRPA1CCR5LMNACHIT1SSTR1 | |
| SCHEMBL27927268 | 0.77 | TRPA1 (0.42) | TRPA1CCR5LMNAMAPK1CHIT1 | |
| SCHEMBL15641447 | 0.75 | MAPK1 (0.40) | TRPA1CCR5LMNAMAPK1CHIT1 | |
| SCHEMBL15679113 | 0.75 | MAPK1 (0.40) | TRPA1CCR5LMNAMAPK1CHIT1 | |
| SCHEMBL29463798 | 0.74 | TRPA1 (0.36) | TRPA1CCR5LMNATSHRSSTR1 | |
| SCHEMBL8959082 | 0.74 | MAPK1 (0.39) | TRPA1LMNAMAPK1CHIT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0474303-B1 | Process for the preparation of cyclopentane derivatives and intermediates therefor | SHELL INT RESEARCH (NL) | 1996-01-17 | — | — | EP | disclosed |
| US-5151550-A | Cyclopentane derivatives | SHELL RESEARCH LIMITED (GB) | 1992-09-29 | — | — | US | disclosed |
| EP-0474303-A1 | Process for the preparation of cyclopentane derivatives and intermediates therefor | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-11 | — | — | EP | disclosed |