SCHEMBL7417047

SCHEMBL7417047

CC1(C)OC(=O)C(Cc2ccccc2)C(=O)O1

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.66
NPSR1 Q6W5P4 1/20 0.66
MDM2 Q00987 1/20 0.46
CES2 O00748 5/20 0.44
EP300 Q09472 1/20 0.42
CTRB1 P17538 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
TLR9 Q9NR96 1/20 0.40
FASN P49327 1/20 0.40
ELANE P08246 1/20 0.40
CTSG P08311 1/20 0.40
PRTN3 P24158 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3093178 0.86 GLA (0.58) GLANPSR1MDM2HTT
SCHEMBL3103917 0.85 GLA (0.66) GLANPSR1
SCHEMBL16174918 0.84 GLA (0.49) GLANPSR1CES2EP300CTRB1
SCHEMBL9193771 0.84 GLA (0.69) GLANPSR1MDM2CES2
SCHEMBL8530967 0.82 GLA (0.46) GLANPSR1CES2EP300CTRB1
SCHEMBL15647719 0.82 GLA (0.67) GLANPSR1MDM2
SCHEMBL16460894 0.82 GLA (0.67) GLANPSR1MDM2CES2TSHR
SCHEMBL15570301 0.82 GLA (0.67) GLANPSR1MDM2CES2HTT
SCHEMBL16174944 0.82 GLA (0.46) GLANPSR1CES2EP300CTRB1
SCHEMBL16174891 0.81 GLA (0.45) GLANPSR1EP300CTRB1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119039291-A Enalidomide intermediate and preparation method thereof 南京药坦生物科技有限公司 2024-11-29 CN disclosed
US-20230255200-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS VI BASF SE (DE) 2023-08-17 US disclosed
US-20220306677-A1 COMPOSITIONS AND METHODS FOR MAKING HYBRID POLYPEPTIDES YALE UNIVERSITY 2022-09-29 US disclosed
WO-2020247605-A1 COMPOSITIONS AND METHODS FOR MAKING HYBRID POLYPEPTIDES YALE UNIVERSITY (US) 2020-12-10 WO disclosed
WO-2020247605-A1 COMPOSITIONS AND METHODS FOR MAKING HYBRID POLYPEPTIDES YALE UNIVERSITY (US) 2020-12-10 WO disclosed
US-9611410-B2 Adhesive resin composition, laminate, and self-stripping method MITSUI CHEMICALS TOHCELLO, INC. (JP) 2017-04-04 US disclosed
US-20160370523-A1 POLARIZING PLATE COMPOSITION, POLARIZING PLATE PROTECTIVE FILM, POLARIZER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-20160370523-A1 POLARIZING PLATE COMPOSITION, POLARIZING PLATE PROTECTIVE FILM, POLARIZER, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2016-12-22 US disclosed
US-9507067-B2 Polarizing plate and liquid crystal display device including the same FUJIFILM CORPORATION (JP) 2016-11-29 US disclosed
US-9507067-B2 Polarizing plate and liquid crystal display device including the same FUJIFILM CORPORATION (JP) 2016-11-29 US disclosed
US-8795539-B2 Block copolymer and method of forming patterns by using the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-08-05 US disclosed
US-20120080404-A1 BLOCK COPOLYMER AND METHOD OF FORMING PATTERNS BY USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2012-04-05 US disclosed
US-20120080404-A1 BLOCK COPOLYMER AND METHOD OF FORMING PATTERNS BY USING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2012-04-05 US disclosed
US-20100323964-A1 NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES ITALFARMACO SPA (IT) 2010-12-23 US disclosed
US-5438118-A Peptide mimics having constrained peptide backbone SMITHKLINE BEECHMAN CORP. (US) 1995-08-01 US disclosed
EP-0578849-B1 Process for the preparation of 1,3-dioxane-4,6-dione derivates BIOGAL GYOGYSZERGYAR (HU) 1995-05-17 EP disclosed
EP-0559793-A4 1994-04-27 EP disclosed
EP-0578849-A1 Process for the preparation of 1,3-dioxane-4,6-dione derivates BIOGAL GYOGYSZERGYAR (HU) 1994-01-19 EP disclosed
EP-0559793-A1 HIV PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1993-09-15 EP disclosed
WO-1992009297-A1 HIV PROTEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 1992-06-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220306677-A1 COMPOSITIONS AND METHODS FOR MAKING HYBRID POLYPEPTIDES NSUN3, TARBP1, TRDMT1 GLA 1992/4885NPSR1 3206/4885MDM2 2753/4885
US-20100323964-A1 NEW NON-SELECTIVE SOMATOSTATIN ANALOGUES SSTR4, SSTR1, SSTR3 GLA 2323/4885NPSR1 37/4885MDM2 4719/4885
US-20230255200-A1 USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS VI COX5B, SQOR, COX6B1 GLA 3342/4885NPSR1 3082/4885MDM2 1775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.