Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12937868 | 0.82 | POLB (0.67) | POLBGAACA12CA1CA2 | |
| SCHEMBL6756690 | 0.80 | POLB (1.00) | POLBGAAL3MBTL1HPGDALOX15 | |
| SCHEMBL31232896 | 0.80 | POLB (1.00) | POLBGAAL3MBTL1HPGDALOX15 | |
| SCHEMBL8796147 | 0.80 | CA12 (0.48) | POLBGAACA12CA1CA2 | |
| SCHEMBL11046075 | 0.78 | POLB (0.70) | POLBGAAL3MBTL1HPGDALOX15 | |
| SCHEMBL7166722 | 0.78 | POLB (0.82) | POLBGAAL3MBTL1HPGDALOX15 | |
| SCHEMBL23091737 | 0.78 | POLB (0.56) | POLBGAAL3MBTL1HPGDALOX15 | |
| SCHEMBL29712500 | 0.78 | POLB (0.56) | POLBGAAL3MBTL1HPGDALOX15 | |
| SCHEMBL7165895 | 0.77 | POLB (0.60) | POLBGAAL3MBTL1HPGDNPSR1 | |
| SCHEMBL8824585 | 0.75 | PGK1 (0.74) | CA12CA9PGK1PGK2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500417-A | ANTIARTHRITIC | THE UPJOHN COMPANY (US) | 1996-03-19 | — | — | US | claimed |
| EP-0661978-A1 | ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1995-07-12 | — | — | EP | claimed |
| WO-1994007501-A1 | ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1994-04-14 | — | — | WO | claimed |