Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214240 | 0.84 | PTGS1 (0.55) | POLBPTGS1MEN1CYP2D6KMT2A | |
| SCHEMBL6756690 | 0.83 | POLB (1.00) | POLBGAAL3MBTL1HPGDALOX15 | |
| SCHEMBL31232896 | 0.83 | POLB (1.00) | POLBGAAL3MBTL1HPGDALOX15 | |
| SCHEMBL11047286 | 0.81 | POLB (0.58) | POLBGAAL3MBTL1KMT2AHPGD | |
| SCHEMBL8740658 | 0.79 | PGK1 (0.65) | PTGS1MEN1CYP2D6KMT2AALOX5 | |
| SCHEMBL8959005 | 0.78 | POLB (0.67) | POLBGAAL3MBTL1MEN1KMT2A | |
| SCHEMBL12937868 | 0.78 | POLB (0.67) | POLBGAAL3MBTL1MEN1KMT2A | |
| SCHEMBL1011551 | 0.76 | MAPK1 (0.60) | POLBGAAL3MBTL1HPGDMAPK1 | |
| SCHEMBL7166722 | 0.75 | POLB (0.82) | POLBGAAL3MBTL1MEN1KMT2A | |
| SCHEMBL7868112 | 0.75 | POLB (0.53) | POLBMEN1KMT2AHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472577-A | CATALYTIC HYDROGENATION OF ALPHA-OXO-PHOSPHONIC ACID ESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1984-09-18 | — | — | US | disclosed |
| EP-0071126-B1 | PROCESS FOR THE MANUFACTURE OF ALDEHYDES | BAYER AG (DE) | 1984-09-12 | — | — | EP | disclosed |
| US-4471118-A | Preparation of aldehydes by heating an α-hydroxyphosphonic acid ester | BAYER AKTIENGESELLSCHAFT (DE) | 1984-09-11 | — | — | US | disclosed |
| EP-0071805-A2 | Process for the preparation of alpha-hydroxy-phosphonic-acid esters | BAYER AG (DE) | 1983-02-16 | — | — | EP | disclosed |
| EP-0071126-A1 | Process for the manufacture of aldehydes | BAYER AG (DE) | 1983-02-09 | — | — | EP | disclosed |