Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 6/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165273 | 0.87 | GLA (0.39) | MEN1KMT2A | |
| SCHEMBL4542812 | 0.83 | IDO1 (0.43) | IDO1AGXTMAOBTAAR1 | |
| SCHEMBL29938481 | 0.83 | IDO1 (0.43) | IDO1AGXTMAOBTAAR1 | |
| SCHEMBL8959078 | 0.80 | IDO1 (0.47) | IDO1MAOBTAAR1KDM4EMAOA | |
| SCHEMBL31126607 | 0.79 | CYP4F2 (0.39) | MEN1KMT2A | |
| SCHEMBL11707522 | 0.79 | GABRA1 (0.46) | TAAR1KDM4EKMT2A | |
| SCHEMBL31126533 | 0.79 | CYP4F2 (0.39) | MEN1KMT2A | |
| SCHEMBL4990438 | 0.78 | VNN1 (0.42) | IDO1AGXTMAOBMEN1KMT2A | |
| SCHEMBL894077 | 0.77 | GAA (0.39) | IDO1AGXTMAOBTAAR1GAA | |
| SCHEMBL563700 | 0.77 | HPGD (0.48) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500417-A | ANTIARTHRITIC | THE UPJOHN COMPANY (US) | 1996-03-19 | — | — | US | claimed |
| EP-0661978-A1 | ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1995-07-12 | — | — | EP | claimed |
| WO-1994007501-A1 | ARYLMETHYLPHOSPHONATES AND PHOSPHONIC ACIDS USEFUL AS ANTI-INFLAMMATORY AGENTS | THE UPJOHN COMPANY (US) | 1994-04-14 | — | — | WO | claimed |