SCHEMBL8959042

SCHEMBL8959042

CC(C)Oc1ccc(OCCN)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 4/20 0.50
PLAU P00749 3/20 0.48
GLA P06280 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PPARD Q03181 2/20 0.46
PPARA Q07869 2/20 0.46
FFAR4 Q5NUL3 1/20 0.42
HPGD P15428 1/20 0.41
NLRP1 Q9C000 1/20 0.41
RORC P51449 1/20 0.39
MAPT P10636 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959153 0.87 GLA (0.48) CSNK2A1PLAUGLASMN1; SMN2PPARD
SCHEMBL27724004 0.82 SMN1; SMN2 (0.46) CSNK2A1PLAUGLASMN1; SMN2PPARD
SCHEMBL19612249 0.79 CSNK2A1 (0.58) CSNK2A1SMN1; SMN2HPGDRORCKDM4E
SCHEMBL8959091 0.76 LTA4H (0.46) CSNK2A1GLASMN1; SMN2PPARDPPARA
SCHEMBL10850125 0.76 TAAR1 (0.54) SMN1; SMN2KDM4E
SCHEMBL8959117 0.75 LTA4H (0.62) GLASMN1; SMN2PPARDPPARAKDM4E
SCHEMBL22809496 0.75 PPARA (0.50) CSNK2A1GLASMN1; SMN2PPARDPPARA
SCHEMBL18924248 0.75 MAPT (0.59) CSNK2A1GLASMN1; SMN2HPGDMAPT
SCHEMBL3453883 0.74 S1PR4 (0.54) CSNK2A1HPGDMAPT
SCHEMBL8959084 0.74 PPARA (0.56) GLASMN1; SMN2PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed