SCHEMBL8959305

SCHEMBL8959305

CC1(C)CC2CC=C(C(=O)O)C=C2O1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 15/20 0.34
HCAR2 Q8TDS4 2/20 0.32
HCAR3 P49019 1/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6974943 0.69 GABRR1 (0.31)
SCHEMBL8874669 0.64 GABRR1 (0.39)
SCHEMBL6661057 0.62
SCHEMBL15088575 0.61 CCR2 (0.36) CCR2
SCHEMBL6045137 0.61 MEN1 (0.40) CCR2HCAR2HCAR3MEN1KMT2A
SCHEMBL21337596 0.60 CCR2 (0.33) CCR2
SCHEMBL17636189 0.59
SCHEMBL31486706 0.59
SCHEMBL19892097 0.59 CCR2 (0.36) CCR2
SCHEMBL13645400 0.59 CCR2 (0.33) CCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693486-A1 Insecticidal N-substituted-N'-(optionally substituted)-N,N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1996-01-24 EP disclosed
US-5482962-A Insecticidal N,N'-disubstituted-N-N'-diacylhydrazines ROHM AND HAAS COMPANY (US) 1996-01-09 US disclosed