Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | FBP1 | P09467 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928266 | 0.79 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPTLMNACTSB | |
| SCHEMBL3920360 | 0.76 | TDP1 (0.48) | ALDH1A1TDP1CTSBMAPK1TSHR | |
| SCHEMBL6362482 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPTLMNACTSB | |
| SCHEMBL930320 | 0.75 | ALDH1A1 (0.46) | ALDH1A1FBP1TDP1MAPTLMNA | |
| SCHEMBL2768608 | 0.72 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPTLMNAMAPK1 | |
| SCHEMBL29764388 | 0.72 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPTLMNAMAPK1 | |
| SCHEMBL8352901 | 0.72 | FBP1 (0.39) | ALDH1A1FBP1TDP1MAPTLMNA | |
| SCHEMBL30954324 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LMNACYP3A4P2RX7 | |
| SCHEMBL15826676 | 0.72 | ALDH1A1 (0.38) | ALDH1A1LMNAKMT2AP2RX7 | |
| SCHEMBL29415604 | 0.72 | ALDH1A1 (0.39) | ALDH1A1LMNACYP3A4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0578735-B1 | NOVEL KERATIN FIBRE DYEING METHOD USING AMINOINDOLES, WITH ACID pH, COMPOSITIONS THEREFOR AND NOVEL AMINOINDOLE COMPOUNDS | OREAL (FR) | 1996-01-03 | — | — | EP | claimed |