Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.54 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 4/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 4/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.31 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7325755 | 0.93 | ITGB3 (0.56) | ITGB3ITGA2BFFAR1GABRG2GABRB3 | |
| Trifluoroacetic Acid SCHEMBL8959450 | 0.87 | ITGB3 (0.66) | ITGB3ITGA2BFFAR1 | |
| SCHEMBL7322487 | 0.87 | ITGB3 (0.50) | ITGB3ITGA2BGABRG2GABRB3GABRA5 | |
| SCHEMBL7320884 | 0.87 | ITGB3 (0.73) | ITGB3ITGA2BGABRG2GABRB3GABRA5 | |
| SCHEMBL7324548 | 0.86 | ITGB3 (0.57) | ITGB3ITGA2BHDAC1HDAC6 | |
| SCHEMBL7332360 | 0.86 | ITGB3 (0.49) | ITGB3ITGA2BGABRG2GABRB3GABRA5 | |
| SCHEMBL7331761 | 0.84 | ITGB3 (0.40) | ITGB3ITGA2BGABRG2GABRB3GABRA5 | |
| SCHEMBL9009354 | 0.83 | ITGB3 (0.63) | ITGB3ITGA2BGABRG2GABRB3GABRA5 | |
| SCHEMBL9009507 | 0.81 | ITGB3 (0.42) | ITGB3ITGA2BGABRG2GABRB3GABRA5 | |
| Trifluoroacetic Acid SCHEMBL7325747 | 0.80 | ITGB3 (0.68) | ITGB3ITGA2BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-B1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR | GENENTECH INC (US) | 1996-01-24 | — | — | EP | disclosed |