Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 4/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7363243 | 0.91 | ITGB3 (0.55) | ITGB3ITGA2BHDAC1HDAC2HDAC8 | |
| Trifluoroacetic Acid SCHEMBL9009502 | 0.88 | ITGB3 (0.51) | ITGB3ITGA2BMDM2HDAC1HDAC2 | |
| SCHEMBL8959452 | 0.81 | ITGB3 (0.54) | ITGB3ITGA2BHDAC1HDAC6GABRA1 | |
| SCHEMBL8959427 | 0.81 | ITGB3 (0.41) | ITGB3ITGA2BHDAC1HDAC2HDAC8 | |
| SCHEMBL7325755 | 0.80 | ITGB3 (0.56) | ITGB3ITGA2BHDAC1HDAC6GABRA1 | |
| Trifluoroacetic Acid SCHEMBL7363241 | 0.79 | ITGB3 (0.66) | ITGB3ITGA2BMDM2HDAC1HDAC2 | |
| SCHEMBL9009406 | 0.79 | ITGB3 (0.61) | ITGB3ITGA2BGABRA1GABRG2GABRB3 | |
| SCHEMBL7356626 | 0.79 | SIRT2 (0.35) | CHRM5GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7330016 | 0.78 | ITGB3 (0.44) | ITGB3ITGA2BMDM2CA12CA1 | |
| SCHEMBL7325550 | 0.78 | ITGB3 (0.46) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565449-A | PLATELET AGGREGATION INHIBITORS | GENENTECH, INC. (US) | 1996-10-15 | — | — | US | disclosed |