Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357560 | 1.00 | KDM4E (0.41) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| Trifluoroacetic Acid SCHEMBL7323735 | 0.95 | KDM4E (0.37) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| Trifluoroacetic Acid SCHEMBL7327519 | 0.95 | KDM4E (0.37) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| Trifluoroacetic Acid SCHEMBL7330241 | 0.94 | KDM4E (0.38) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7354810 | 0.87 | ITGB3 (0.41) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7323744 | 0.87 | ITGB3 (0.30) | ITGB3ITGA2B | |
| SCHEMBL7327527 | 0.87 | ITGB3 (0.30) | ITGB3ITGA2B | |
| SCHEMBL7330251 | 0.86 | ITGB3 (0.31) | KDM4EALOX15TSHRSIRT1ITGB3 | |
| SCHEMBL7363304 | 0.86 | LTB4R (0.32) | SSTR4SSTR5HDAC4HDAC1SSTR2 | |
| SCHEMBL7365574 | 0.86 | ITGB3 (0.46) | KDM4EALOX15TSHRSIRT1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610334-B1 | NONPEPTIDYL INTEGRIN INHIBITORS HAVING SPECIFICITY FOR THE GPII B III A RECEPTOR | GENENTECH INC (US) | 1996-01-24 | — | — | EP | disclosed |