Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8967436 | 0.81 | KDM4E (0.48) | KDM4ESMN1; SMN2KMT2AMEN1NLRP3 | |
| SCHEMBL8959473 | 0.75 | KMT2A (0.40) | KDM4ESMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL12111735 | 0.66 | GABRA1 (0.42) | KDM4ESMN1; SMN2KMT2ANLRP3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL17594819 | 0.63 | NOTUM (0.36) | KDM4ESMN1; SMN2KMT2ATDP1 | |
| SCHEMBL23732711 | 0.63 | PKM (0.41) | SMN1; SMN2HTTNCEH1 | |
| SCHEMBL9656592 | 0.61 | NCEH1 (0.48) | KDM4ESMN1; SMN2KMT2AMEN1NLRP3 | |
| SCHEMBL7005859 | 0.59 | GRIN2D (0.41) | KDM4EALDH1A1HTTPOLB | |
| SCHEMBL15621787 | 0.59 | NCEH1 (0.36) | SMN1; SMN2ALDH1A1HTTNCEH1CYP1A2 | |
| SCHEMBL9658235 | 0.58 | NCEH1 (0.51) | KDM4ESMN1; SMN2KMT2AMEN1NLRP3 | |
| SCHEMBL21180777 | 0.58 | SMN1; SMN2 (0.41) | KDM4ESMN1; SMN2ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0693477-A1 | Hydroxypyridonecarboxylic acid amides, their preparation and use | BASF AKTIENGESELLSCHAFT (DE) | 1996-01-24 | — | — | EP | disclosed |