Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HAT1 | O14929 | 4/20 | 0.39 |
| ▸ | EP300 | Q09472 | 4/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959856 | 1.00 | MAPT (0.51) | MAPTHPGDNPC1RAB9ATDP1 | |
| SCHEMBL8959819 | 0.83 | MAPT (0.58) | MAPTHPGDHAT1EP300GABRA1 | |
| SCHEMBL9289530 | 0.81 | MAPT (0.56) | MAPTHPGDHAT1EP300GABRA1 | |
| SCHEMBL8959728 | 0.78 | PTGS1 (0.43) | — | |
| SCHEMBL8959730 | 0.78 | PTGS1 (0.43) | — | |
| SCHEMBL9159676 | 0.77 | MAPT (0.48) | MAPTHPGDNPC1RAB9ATDP1 | |
| SCHEMBL8959679 | 0.77 | SRD5A1 (0.55) | — | |
| SCHEMBL8959688 | 0.77 | SRD5A1 (0.55) | — | |
| SCHEMBL8959956 | 0.74 | NPC1 (0.68) | MAPTHPGDNPC1RAB9ATDP1 | |
| SCHEMBL8959963 | 0.74 | NPC1 (0.68) | MAPTHPGDNPC1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530019-A | FOR TREATMENT OF PROSTATE GLAND DISORDERS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |